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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR2 All Species: 25.45
Human Site: Y1520 Identified Species: 62.22
UniProt: Q14571 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14571 NP_002214.2 2701 308064 Y1520 L Q S A F R I Y N C T W P N P
Chimpanzee Pan troglodytes XP_518409 2650 301859 L1504 L Q S T T R L L E C P W L Q Q
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 Y1519 L Q S A F R I Y N C T W P N P
Dog Lupus familis XP_852399 2701 308021 Y1520 L Q S A F R I Y N C T W P N P
Cat Felis silvestris
Mouse Mus musculus Q9Z329 2701 307428 Y1520 L Q S A F R I Y N C T W P N P
Rat Rattus norvegicus P29995 2701 307040 Y1520 L Q S A F R I Y N C T W P N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235613 2701 307518 Y1522 L Q S A F R I Y N C T W P N P
Frog Xenopus laevis NP_001084015 2693 306654 Q1497 T R Q P V F V Q L L Q A I F R
Zebra Danio Brachydanio rerio XP_691057 2588 295620 G1457 D M A T V S I G P T D R K N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 T1623 L Q A A H R I T Q C R W L S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.5 99.4 97.8 N.A. 95.7 95.3 N.A. N.A. 92 69.1 72.7 N.A. 55.2 N.A. N.A. N.A.
Protein Similarity: 100 76.3 99.7 98.9 N.A. 98 97.6 N.A. N.A. 95.3 81.9 82.8 N.A. 70.2 N.A. N.A. N.A.
P-Site Identity: 100 40 100 100 N.A. 100 100 N.A. N.A. 100 0 13.3 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 46.6 100 100 N.A. 100 100 N.A. N.A. 100 13.3 20 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 70 0 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 60 10 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 80 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 80 0 0 0 0 0 10 10 10 10 0 0 20 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 60 0 0 0 0 70 0 % N
% Pro: 0 0 0 10 0 0 0 0 10 0 10 0 60 0 60 % P
% Gln: 0 80 10 0 0 0 0 10 10 0 10 0 0 10 10 % Q
% Arg: 0 10 0 0 0 80 0 0 0 0 10 10 0 0 10 % R
% Ser: 0 0 70 0 0 10 0 0 0 0 0 0 0 10 0 % S
% Thr: 10 0 0 20 10 0 0 10 0 10 60 0 0 0 0 % T
% Val: 0 0 0 0 20 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _